en
  • Deutsch - de
  • English - en
  • Clinical research
      Interdisciplinary pediatric study center (Hauner iPSC)
        Ped-COVID-19 Study
          Michael Albert
            Scivias Study
              TRACE Study
                ImmGenDC Study
                  Hematology/Oncology/Coagulation
                • Research Labs
                    Binder Lab
                      Bohlen Lab
                        Braun Lab
                          Gaertner Lab
                            Griese Lab
                              Hauck Lab
                                Hübner Lab
                                  Jeremias lab
                                    Kim-Hellmuth Lab
                                      Klein Lab
                                        Koletzko Lab
                                          Kotlarz Lab
                                            Lange-Sperandio Lab
                                              von Mutius Lab
                                                Nußbaum Lab
                                                  Rosenecker Lab
                                                    Schaub Lab
                                                      Schmid Lab
                                                        Schwerd Lab
                                                      • PhD Program
                                                      • Technology platforms
                                                          Bioinformatics
                                                            Flow Cytometry
                                                              High throughput sequencing
                                                                Microscopy
                                                                  Pre-GMP Facility
                                                                    Mass spectrometry
                                                                      Hauner Biobank
                                                                        Organoid Lab
                                                                          Humangenetik am Hauner
                                                                        • News/Events
                                                                            News
                                                                              Rare Disease Day
                                                                                ECHO-Meeting
                                                                                  Meinhard von Pfaundler-Lectures
                                                                                    Klaus Betke Symposium
                                                                                  • Join us!
                                                                                  1. CCRC-HaunerEN
                                                                                  2. Technology platforms
                                                                                  3. Organoid Lab

                                                                                  Organoid Lab

                                                                                  The Klein Lab established a dedicated well-equipped lab space to work on human induced pluripotent stem cell (iPSC)-derived organoids, currently focussing on a novel method for iPSC-derived bone marrow organoids.

                                                                                  Contact

                                                                                  Stephanie Frenz-Wießner, MD, PhD

                                                                                  Klein Lab - Head of Organoid Lab 

                                                                                  ✉ stephanie.frenz@med.uni-muenchen.de

                                                                                  Room: KU.10

                                                                                  Martina Kalauz

                                                                                  Klein Lab - Technician

                                                                                  ✉ martina.kalauz@med.uni-muenchen.de

                                                                                  Room: KU.10

                                                                                  News

                                                                                  Successful BaCell 3D – Organoid Conference: Stephanie Frenz-Wießner Wins Best Oral Presentation Award

                                                                                  At the prestigious BaCell 3D - Organoid Conference, Stephanie Frenz-Wießner received the coveted Best Oral Presentation Award for her outstanding presentation. The conference, which focuses on advanced organoid technologies, attracted experts and researchers from around the world.

                                                                                  In addition to her achievement, Stephanie Frenz-Wießner is pictured with the poster presentation winners, who were also recognized for their outstanding scientific contributions. For more information on the conference, please visit www.bacell3d.com.

                                                                                  Bone marrow in miniature

                                                                                  Organoids - three-dimensional miniature models of organs - are less than a millimetre in size. Ideally, they should be able to replicate the functions of their larger counterparts. An interdisciplinary team of scientists at the Dr. von Haunerschen Children's Hospital of the LMU has now succeeded in constructing human bone marrow organoids. "We believe that this technology could prove useful in many ways - from modelling congenital and acquired bone marrow diseases to the biotechnological production of blood cells," says Professor Christoph Klein, Director of the LMU Children's Hospital and Children's Polyclinic. In the journal Nature Methods, the team has described in detail their innovative method for generating these complex human bone marrow organoids from induced pluripotent stem cells.

                                                                                  More information: 

                                                                                  https://www.lmu-klinikum.de/aktuelles/pressemitteilungen/ein-knochenmark-im-miniaturformat/b2654d9d92860337

                                                                                  Publication 

                                                                                  Frenz-Wiessner et al., Generation of complex bone marrow organoids from human induced pluripotent stem cells, 2024, Nature Methods.

                                                                                  https://www.nature.com/articles/s41592-024-02172-2 

                                                                                  Research at CCRC Hauner

                                                                                  Contact LMU Klinikum

                                                                                  Contact CCRC Hauner

                                                                                  Haunersches

                                                                                  CCRC Hauner

                                                                                  Kinderklinik und Kinderpoliklinik

                                                                                  im Dr. von Haunerschen Kinderspital

                                                                                  Ludwig Maximilians Universität München

                                                                                  Lindwurmstr. 4

                                                                                  80337 Munich, Germany

                                                                                  ☎ +49-89-4400-57705

                                                                                  Login for editors
                                                                                  Imprint | Data-Safety
                                                                                  en
                                                                                  • Deutsch - de
                                                                                  • English - en

                                                                                  Comprehensiv...

                                                                                  • Clinical research
                                                                                    • Interdisciplinary pediatric study center (Hauner iPSC)
                                                                                    • Ped-COVID-19 Study
                                                                                    • Michael Albert
                                                                                    • Scivias Study
                                                                                    • TRACE Study
                                                                                    • ImmGenDC Study
                                                                                    • Hematology/Oncology/Coagulation
                                                                                  • Research Labs
                                                                                    • Binder Lab
                                                                                    • Bohlen Lab
                                                                                    • Braun Lab
                                                                                    • Gaertner Lab
                                                                                    • Griese Lab
                                                                                    • Hauck Lab
                                                                                    • Hübner Lab
                                                                                    • Jeremias lab
                                                                                    • Kim-Hellmuth Lab
                                                                                    • Klein Lab
                                                                                    • Koletzko Lab
                                                                                    • Kotlarz Lab
                                                                                    • Lange-Sperandio Lab
                                                                                    • von Mutius Lab
                                                                                    • Nußbaum Lab
                                                                                    • Rosenecker Lab
                                                                                    • Schaub Lab
                                                                                    • Schmid Lab
                                                                                    • Schwerd Lab
                                                                                  • PhD Program
                                                                                  • Technology platforms
                                                                                    • Bioinformatics
                                                                                    • Flow Cytometry
                                                                                    • High throughput sequencing
                                                                                    • Microscopy
                                                                                    • Pre-GMP Facility
                                                                                    • Mass spectrometry
                                                                                    • Hauner Biobank
                                                                                    • Organoid Lab
                                                                                    • Humangenetik am Hauner
                                                                                  • News/Events
                                                                                    • News
                                                                                    • Rare Disease Day
                                                                                    • ECHO-Meeting
                                                                                    • Meinhard von Pfaundler-Lectures
                                                                                    • Klaus Betke Symposium
                                                                                  • Join us!