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    3. Organoid Lab

    Organoid Lab

    The Klein Lab established a dedicated well-equipped lab space to work on human induced pluripotent stem cell (iPSC)-derived organoids, currently focussing on a novel method for iPSC-derived bone marrow organoids.

    Contact

    Stephanie Frenz-Wießner, MD, PhD

    Klein Lab - Head of Organoid Lab 

    ✉ stephanie.frenz@med.uni-muenchen.de

    Room: KU.10

    Martina Kalauz

    Klein Lab - Technician

    ✉ martina.kalauz@med.uni-muenchen.de

    Room: KU.10

    News

    Successful BaCell 3D – Organoid Conference: Stephanie Frenz-Wießner Wins Best Oral Presentation Award

    At the prestigious BaCell 3D - Organoid Conference, Stephanie Frenz-Wießner received the coveted Best Oral Presentation Award for her outstanding presentation. The conference, which focuses on advanced organoid technologies, attracted experts and researchers from around the world.

    In addition to her achievement, Stephanie Frenz-Wießner is pictured with the poster presentation winners, who were also recognized for their outstanding scientific contributions. For more information on the conference, please visit www.bacell3d.com.

    Bone marrow in miniature

    Organoids - three-dimensional miniature models of organs - are less than a millimetre in size. Ideally, they should be able to replicate the functions of their larger counterparts. An interdisciplinary team of scientists at the Dr. von Haunerschen Children's Hospital of the LMU has now succeeded in constructing human bone marrow organoids. "We believe that this technology could prove useful in many ways - from modelling congenital and acquired bone marrow diseases to the biotechnological production of blood cells," says Professor Christoph Klein, Director of the LMU Children's Hospital and Children's Polyclinic. In the journal Nature Methods, the team has described in detail their innovative method for generating these complex human bone marrow organoids from induced pluripotent stem cells.

    More information: 

    https://www.lmu-klinikum.de/aktuelles/pressemitteilungen/ein-knochenmark-im-miniaturformat/b2654d9d92860337

    Publication 

    Frenz-Wiessner et al., Generation of complex bone marrow organoids from human induced pluripotent stem cells, 2024, Nature Methods.

    https://www.nature.com/articles/s41592-024-02172-2 

    Research at CCRC Hauner

    Contact LMU Klinikum

    Contact CCRC Hauner

    Haunersches

    CCRC Hauner - Comprehensive Childhood Research Center

    Kinderklinik und Kinderpoliklinik

    im Dr. von Haunerschen Kinderspital

    Ludwig Maximilians Universität München

    Lindwurmstr. 4

    80337 Munich, Germany


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