Plotkin L, Aharoni-Frutkoff Y, Pollak D, Azulay A, Shavit Z, Focht G, Livovsky J, Lev-Tzion R, Koslowsky B, Boneh RS, Weiss B, Slae M, Dotan I, Godny L, Kierkuś J, Garwolińska M, Broide E, Moshe G, Griffiths AM, Tersigni C, Naftali T, Abramas L, D'arcangelo G, Yerushalmy-Feler A, Schwerd T, Crowley E, Wine E, Yassour M, Reifen R, Turner D. Tasty&Healthy Whole-Food Diet in Asymptomatic Children and Young Adults With Biologically Active Crohn's Disease: The TASTI-E Randomized Controlled Trial Clin Gastroenterol Hepatol. 2026:S1542-3565(26)00433-7 (online ahead of print)
Azulay A, Gotesdyner L, Aharoni-Frutkoff Y, Focht G, Talmor Y, Borenstein E, Plotkin L, Orlanski-Meyer E, Lev-Tzion R, Ledder O, Yogev D, Assa A, Broide E, Yerushalmy-Feler A, Kierkuś J, Schwerd T, Wine E, Turner D. Multi-omics-based machine learning model predicts response and guides treatment in Crohn disease: a case study in nutritional therapy Inflamm Bowel Dis. 2026;32:1513-1523
Wei X, Degen S, Hironimus T, Rechenauer T, Yankouskaya K, Rückel A, Schmid M, Rieger D, Ehrsam C, Regensburger AP, Schnell A, Rabe A, Schmidt-Choudhury A, Tannapfel A, De Laffolie J, Schumann S, Schwerd T, Hoelz H, Allabauer I, Gupta P, Krebs W, Hartmann A, Woelfle J, Rieker R, Hoerning A. PSMB8 stratifies therapy response in eosinophilic esophagitis Clin Exp Immunol. 2026;220(1):uxag012
Vuijk SA, Klomberg RCW, Schwerd T, Griffiths AM, Hussey S, Carroll MW, Malmborg P, Deb P, Wessels M, Mouratidou N, van Biervliet S, Friedt M, Minson S, Vrieling-Prince FHM, Croft NM, de Ridder L Significant kidney impairment in pediatric inflammatory bowel disease and practice points for pediatric gastroenterologists 2026;82:1251-1260
Frank ML, Thi TGL, Schacker I, Bragagna L, Geist M, Buehler S, Riedl V, Koletzko S, Schwerd T, Hoelz H. Real-world data on STRIDE-II treatment targets in a pediatric cohort with inflammatory bowel disease J Pediatr Gastroenterol Nutr. 2026;82:1006-1018
Atia O, Azulay A, Focht G, Ledder O, Lev-Tzion R, Schwerd T, Siebert K, Faro T, Chapuy L, Groleau V, Grzywacz K, Amar S, Moalem B, Michailevitch R, Bergel M, Norsa L, Aloi M, Kubat M, Bronsky J, Walsh PT, Hussey S, Ben-Zvi D, Turner D. Gene expression profile predicts response to antitumor necrosis factor in children with Crohn's disease: A Porto group biobank study, and a systematic review. J Pediatr Gastroenterol Nutr. 2025; 81:1189-1196
Csollarova K, Koletzko L, Le Thi TG, Wratil PR, Zhelyazkova A, Breiteneicher S, Stern M, Lupoli G, Schwerd T, Choukér A, Hornung V, Keppler OT, Adorjan K, Török HP, Koletzko S Factors Associated with Impaired Humoral Immune Response to mRNA Vaccines in Patients with Inflammatory Bowel Disease: A Matched-Cohort Analysis from the RisCoin Study. Vaccines. 2025:13:673
Siebert K, Faro T, Köhler N, Hölz H, Jarosch S, Matchado M, Häcker D, De Zen F, Hajji MS, Lurz E, Koletzko S, Pauling JK, Steiger K, Neuhaus K, Ohnmacht C, List M, Busch DH, Haller D, Schwerd T. Endoscopic healing in pediatric IBD perpetuates a persistent signature defined by Th17 cells with molecular and microbial drivers of disease Cell Rep Med. 2025;6:102236
Lenz D, Abdulaziz M, Peters B, Wagner M, Schlieben LD, Corman VM, Baumann U, Bufler P, Dattner T, Ganschow R, Genzel K, Hammann N, Hartleif S, Hegen B, Henning S, Hoerning A, Jankofsky M, Junge N, Kathemann S, Knoppke B, Kohl-Sobania M, Laass M, Lainka E, Lurz E, Melter M, Müller H, Pilic D, Ries M, Schiefele L, Schwerd T, Sturm E, Wegner M, Urschitz MS, Garbade SF, Wenning D, Drosten C, Fichtner A, Kölker S, Hoffmann GF, Prokisch H, Staufner C. Paediatric acute liver failure: A prospective, nationwide, population-based surveillance study in Germany J Pediatr Gastroenterol Nutr. 2025;81:653-662
- Aldrian D, Pollio A, Mayerhofer C, Diederen K, Jacobs JP, Pai N, Szamosi JC, Hart L, Turner D, Del Chierico F, Cardile S, Grigoryan Z, Chen LA, Hurych J, Cinek O, Taddei CR, Schwerd T, Wine E, Griffiths AM, Müller T, Vogel GF. Fecal Microbial Community Profiling Allows Discrimination of Phenotype and Treatment Response in Pediatric Crohn's Disease and Ulcerative Colitis-An International Meta-Analysis Inflamm Bowel Dis. 2025;31:2338-2351
Aharoni-Frutkoff Y, Plotkin L, Pollak D, Livovsky J, Focht G, Lev-Tzion R, Ledder O, Assa A, Yogev D, Orlanski-Meyer E, Broide E, Kierkuś J, Kang B, Weiss B, Aloi M, Schwerd T, Shouval DS, Bramuzzo M, Griffiths AM, Yassour M, Turner D. Whole Food Diet Induces Remission in Children and Young Adults With Mild to Moderate Crohn's Disease and Is More Tolerable Than Exclusive Enteral Nutrition: A Randomized Controlled Trial. Gastroenterology. 2025;169:1462-1474.
Häcker D, Siebert K, Smith BJ, Köhler N, Riva A, Mahapatra A, Heimes H, Nie J, Metwaly A, Hölz H, Manz Q, De Zen F, Heetmeyer J, Socas K, Le Thi G, Meng C, Kleigrewe K, Pauling JK, Neuhaus K, List M, Pollard KS, Schwerd T, Haller D. Exclusive enteral nutrition initiates individual protective microbiome changes to induce remission in pediatric Crohn's disease. Cell Host Microbe. 2024;32(11):2019-2034.
Hölz H, Faro T, Frank ML, Forné I, Kugelmann D, Jurk A, Buehler S, Siebert K, Matchado M, Straub T, Hering A, Piontek G, Mueller S, Koletzko S, List M, Steiger K, Rudelius M, Waschke J, Schwerd T. Persistent desmoglein-1 downregulation and periostin accumulation in histologic remission of eosinophilic esophagitis. J Allergy Clin Immunol 2025;155:505-519
Guz-Mark A, Aloi M, Scarallo L, Bramuzzo M, Escher JC, Alvisi P, Henderson P, Hojsak I, Lev-Tzion R, El-Matary W, Schwerd T, Granot M, Sladek M, Strisciuglio C, Müller KE, Olbjørn C, Tzivinikos C, Yerushalmy-Feler A, Huysentruyt K, Norsa L, Viola I, de Ridder L, Shouval DS, Lega S, Lionetti P, Catassi G, Assa A; Porto IBD working group of ESPGHAN. Infantile and Very Early Onset Inflammatory Bowel Disease: A Multicenter Study. Pediatrics. 2024;154:e2023064546.
Hölz H, Bragagna L, Litwin A, Koletzko S, Le Thi TG, Schwerd T. Pediatric IBD Patients Treated With Infliximab and Proactive Drug Monitoring Benefit From Early Concomitant Immunomodulatory Therapy: A Retrospective Analysis of a 10-Year Real-Life Cohort. Inflammatory Bowel Diseases 2024;30:2004–2018
Koletzko S, Le Thi TG, Zhelyazkova A, Osterman A, Wichert SP, Breiteneicher S, Koletzko L, Schwerd T, Völk S, Jebrini T, Horak J, Tuschen M, Choukér A, Hornung V, Keppler OT, Koletzko B, Török HP, Adorjan K; Members of Riscoin Study Group. A prospective longitudinal cohort study on risk factors for COVID-19 vaccination failure (RisCoin): methods, procedures and characterization of the cohort. Clin Exp Med 2023;23:4901-4917.
Hoelz H, Heetmeyer J, Tsakmaklis A, Hiergeist A, Siebert K, De Zen F, Häcker D, Metwaly A, Neuhaus K, Gessner A, Vehreschild MJGT, Haller D, Schwerd T. Is Autologous Fecal Microbiota Transfer after Exclusive Enteral Nutrition in Pediatric Crohn's Disease Patients Rational and Feasible? Data from a Feasibility Test. Nutrients. 2023;15:1742.
Metwaly A, Jovic J, Waldschmitt N, Khaloian S, Heimes H, Häcker D, Ahmed M, Hammoudi N, Le Bourhis L, Mayorgas A, Siebert K, Basic M, Schwerd T, Allez M, Panes J, Salas A, Bleich A, Zeissig S, Schnupf P, Cominelli F, Haller D. Diet prevents the expansion of segmented filamentous bacteria and ileo-colonic inflammation in a model of Crohn's disease. Microbiome. 2023;11:66.
Strigli A, Gopalakrishnan S, Zeissig Y, Basic M, Wang J, Schwerd T, Doms S, Peuker K, Hartwig J, Harder J, Hönscheid P, Arnold P, Kurth T, Rost F, Petersen BS, Forster M, Franke A, Kelsen JR, Rohlfs M, Klein C, Muise AM, Warner N, Nambu R, Mayerle J, Török HP, Linkermann A, Muders MH, Baretton GB, Hampe J, Aust DE, Baines JF, Bleich A, Zeissig S. Deficiency in X-linked inhibitor of apoptosis protein promotes susceptibility to microbial triggers of intestinal inflammation. Sci Immunol. 2021;6:eabf7473.
Koletzko L, Klucker E, Le Thi TG, Breiteneicher S, Rubio-Acero R, Neuhaus L, Stark RG, Standl M, Wieser A, Török H, Koletzko S, Schwerd T. Following Pediatric and Adult IBD Patients through the COVID-19 Pandemic: Changes in Psychosocial Burden and Perception of Infection Risk and Harm over Time. J Clin Med. 2021;10, 4124;
Brückner A, Werkstetter KJ, Frivolt K, Shokry E, Ahmed M, Metwaly A, Marques JG, Uhl O, Krohn K, Hajji M, Otte S, Pozza SB, Bufler P, Liptay S, Haller D, Koletzko B, Koletzko S, Schwerd T. Partial enteral nutrition has no benefit on bone health but improves growth in paediatric patients with quiescent or mild Crohn's disease. Clin Nutr. 2020;39:3786-3796.
Serra EG, Schwerd T, Moutsianas L, Cavounidis A, Fachal L, Pandey S, Kammermeier J, Croft NM, Posovszky C, Rodrigues A, Russell RK, Barakat F, Auth MKH, Heuschkel R, Zilbauer M, Fyderek K, Braegger C, Travis SP, Satsangi J, Parkes M, Thapar N, Ferry H, Matte JC, Gilmour KC, Wedrychowicz A, Sullivan P, Moore C, Sambrook J, Ouwehand W, Roberts D, Danesh J, Baeumler TA, Fulga TA, Karaminejadranjbar M, Ahmed A, Wilson R, Barrett JC, Elkadri A, Griffiths AM, investigators CiIg, Oxford IBDcsi, Study I, Swiss IBDci, Consortium UIG, Consortium NIG, Snapper SB, Shah N, Muise AM, Wilson DC, Uhlig HH, Anderson CA. Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease. Nat Commun 2020;11:995.
Schwerd T, Bryant RV, Pandey S, Capitani M, Meran L, Cazier JB, Jung J, Mondal K, Parkes M, Mathew CG, Fiedler K, McCarthy DJ, Consortium WGS, Oxford IBDcsi, investigators CiIg, Consortium UIG, Sullivan PB, Rodrigues A, Travis SPL, Moore C, Sambrook J, Ouwehand WH, Roberts DJ, Danesh J, Study I, Russell RK, Wilson DC, Kelsen JR, Cornall R, Denson LA, Kugathasan S, Knaus UG, Serra EG, Anderson CA, Duerr RH, McGovern DP, Cho J, Powrie F, Li VS, Muise AM, Uhlig HH. NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease. Mucosal Immunol 2018;11:562-574.
Schwerd T, Twigg SRF, Aschenbrenner D, Manrique S, Miller KA, Taylor IB, Capitani M, McGowan SJ, Sweeney E, Weber A, Chen L, Bowness P, Riordan A, Cant A, Freeman AF, Milner JD, Holland SM, Frede N, Muller M, Schmidt-Arras D, Grimbacher B, Wall SA, Jones EY, Wilkie AOM, Uhlig HH. A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis. J Exp Med 2017;214:2547-2562.
Schwerd T, Pandey S, Yang HT, Bagola K, Jameson E, Jung J, Lachmann RH, Shah N, Patel SY, Booth C, Runz H, Duker G, Bettels R, Rohrbach M, Kugathasan S, Chapel H, Keshav S, Elkadri A, Platt N, Muise AM, Koletzko S, Xavier RJ, Marquardt T, Powrie F, Wraith JE, Gyrd-Hansen M, Platt FM, Uhlig HH. Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann-Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease. Gut 2017;66:1060-1073.
Schwerd T, Frivolt K, Clavel T, Lagkouvardos I, Katona G, Mayr D, Uhlig HH, Haller D, Koletzko S, Bufler P. Exclusive enteral nutrition in active pediatric Crohn disease: Effects on intestinal microbiota and immune regulation. J Allergy Clin Immunol 2016;138:592-6.
Schwerd T, Khaled AV, Schurmann M, Chen H, Handel N, Reis A, Gillessen-Kaesbach G, Uhlig HH, Abou Jamra R. A recessive form of extreme macrocephaly and mild intellectual disability complements the spectrum of PTEN hamartoma tumour syndrome. Eur J Hum Genet 2016;24:889-94.
Uhlig HH, Schwerd T, Koletzko S, Shah N, Kammermeier J, Elkadri A, Ouahed J, Wilson DC, Travis SP, Turner D, Klein C, Snapper SB, Muise AM, Group CiIS, Neopics. The diagnostic approach to monogenic very early onset inflammatory bowel disease. Gastroenterology 2014;147:990-1007 e3.
Frivolt K, Schwerd T, Werkstetter KJ, Schwarzer A, Schatz SB, Bufler P, Koletzko S. Repeated exclusive enteral nutrition in the treatment of paediatric Crohn's disease: predictors of efficacy and outcome. Aliment Pharmacol Ther 2014;39:1398-407.
